Influencе of peptides from the bursa of Fabricius in broiler chickens on the functional activity of subpopulations of lymphocytes in immunosuppressed mice

It is known that peptides inhibit the enzymes of viruses and are able to penetrate into cells by their embedding in cell membrane, as a result which penetration host blocked, makes it possible consider an alterna tive antiviral drugs. In this regard, demand for immune-boosting nutraceuticals functional foods containing biologically active growing. The immunomodulating effect were studied on mice BALb/c line suffered from experimentally induced immunodeficiency; got injections isolated bursa Fabricius (bursal sac) broiler chickens. 5 groups formed. animals 1st group (control one) received physiological saline per os placebo, 2 nd bursal at dose 0.02 mg/kg body weight, 3 rd (immunosuppressed) 4 th was administered held control one (immunosuppressed group). Blood tests taken days 1, 7 14 experiment. activity neutrophils determined method spontane ous chemiluminescence. Among immudepressive (the group) day researchers observed decrease CD3+ 55.3%, CD22+ 83.7%, CD3+CD4+ 51.9% CD3+CD8+ 54.6% comparison with intact Administration immunosuppressed increases number subpopulations lymphocytes 126.6%, 381.6%, 8.9% 81.8% compared ani mals, receiving placebo (group 3). Similar results obtained 14th On basis performed studies, can be argued immunocompetent organs chickens (bursa Fabricius) promising source immunotropic peptides.).